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Allison DB, Gadde KM, Garvey WT, et al

At the same time, HCY accumulates in the blood, leading to hyperhomocysteinemia

Two separate human clinical trials have investigated this compound: Ulcerative Colitis Trial Clinical investigation of this compound in patients with ulcerative colitis examined the compounds GI-protective properties properties that are consistent with its gastric origin and documented activity on intestinal permeability barriers in animal models